Frederick (Rick) directs efforts in Genomics Discovery and related new and early ventures. His team uses large scale human genomics, computational biology, and principles of precision medicine to create and evaluate therapeutic hypotheses and sustaining discovery platforms in new and early ventures.
Prior to joining the Foresite team, Rick held positions of increasing responsibility at the Regeneron Genetics Center (RGC). While Head of Translational Genetics at the RGC, he led teams that used large scale human genomics to systematically understand human biology and disease pathogenesis, critically evaluate therapeutic targets in all stages of discovery and development, and discover novel therapeutic targets. His team’s work validated multiple therapeutic targets and created active novel target biology and drug discovery programs across therapeutic areas.
Rick is a board-certified physician-scientist with training in Internal Medicine and Cardiovascular Medicine from Stanford Hospital and Clinics. While at Stanford, he drove the development of analytical and clinical workflows for use of whole exome and genome sequencing in clinical care, and used clinical epidemiology, large scale sequencing, and experimental biology to understand familial cardiovascular disease pathogenesis.
Rick holds an A.B. in Chemistry and Physics from Harvard College and M.D. from Stanford University School of Medicine. His research interests span clinical epidemiology, genomics, computational biology, and implementation science, all with a view towards clinical translation. He is an author of peer-reviewed publications in top-tier journals such as Science, Lancet, JAMA, and New England Journal of Medicine.